4AZ5
Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH
Summary for 4AZ5
Entry DOI | 10.2210/pdb4az5/pdb |
Related | 2YL5 2YL6 2YL8 2YL9 2YLA 2YLL 4AZ6 4AZ7 |
Descriptor | BETA-N-ACETYLHEXOSAMINIDASE, (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Cellular location | Secreted, cell wall ; Peptidoglycan-anchor : P49610 |
Total number of polymer chains | 1 |
Total formula weight | 49066.88 |
Authors | Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2012-06-22, release date: 2013-07-10, Last modification date: 2023-12-20) |
Primary citation | Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11:7907-, 2013 Cited by PubMed: 24132305DOI: 10.1039/C3OB41579A PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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