4AWN

Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate.

4AWN の概要

• エントリーDOI: 10.2210/pdb4awn/pdb
• 分子名称: DEOXYRIBONUCLEASE-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (8 entities in total)
• 機能のキーワード: hydrolase, endonuclease, pulmozyme
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30332.16

構造登録者

Parsiegla, G.,Noguere, C.,Santell, L.,Lazarus, R.A.,Bourne, Y. (登録日: 2012-06-04, 公開日: 2013-01-09, 最終更新日: 2023-12-20)

• 主引用文献: Parsiegla, G.,Noguere, C.,Santell, L.,Lazarus, R.A.,Bourne, Y.; The Structure of Human DNase I Bound to Magnesium and Phosphate Ions Points to a Catalytic Mechanism Common to Members of the DNase I-Like Superfamily.; Biochemistry, 51:10250-, 2012; PubMed: 23215638; DOI: 10.1021/BI300873F

実験手法

X-RAY DIFFRACTION (1.95 Å)