4AWM
Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with (-)-epigallocatechin gallate from green tea
Summary for 4AWM
Entry DOI | 10.2210/pdb4awm/pdb |
Related | 4AVG 4AVL 4AVQ 4AWF 4AWG 4AWH 4AWK |
Descriptor | POLYMERASE PA, MANGANESE (II) ION, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, ... (4 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, hydrolase, manganese-dependent, pd...d-e...k superfamily, hydrolase/inhibitor |
Biological source | INFLUENZA A VIRUS |
Total number of polymer chains | 1 |
Total formula weight | 23495.29 |
Authors | Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S. (deposition date: 2012-06-04, release date: 2012-08-22, Last modification date: 2023-12-20) |
Primary citation | Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S. Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8:2831-, 2012 Cited by PubMed: 22876177DOI: 10.1371/JOURNAL.PPAT.1002831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report