4AVP
Crystal structure of the DNA-binding domain of human ETV1.
Summary for 4AVP
| Entry DOI | 10.2210/pdb4avp/pdb |
| Descriptor | ETS TRANSLOCATION VARIANT 1, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | transcription, transcriptional activation and repression, dna binding protein, e twenty-six, erwing sarcoma, prostate cancer, melanoma, gastrointestinal stromal tumour |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 4 |
| Total formula weight | 49872.97 |
| Authors | Allerston, C.K.,Cooper, C.D.O.,Krojer, T.,Chaikuad, A.,Filippakopoulos, P.,Canning, P.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Gileadi, O. (deposition date: 2012-05-28, release date: 2012-06-20, Last modification date: 2023-12-20) |
| Primary citation | Cooper, C.D.O.,Newman, J.A.,Aitkenhead, H.,Allerston, C.K.,Gileadi, O. Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290:13692-, 2015 Cited by PubMed: 25866208DOI: 10.1074/JBC.M115.646737 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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