4AVL

Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP

Summary for 4AVL

• Entry DOI: 10.2210/pdb4avl/pdb
• Related: 4AVG
• Descriptor: POLYMERASE PA, MANGANESE (II) ION, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total)
• Functional Keywords: hydrolase, endonuclease, manganese-dependent
• Biological source: INFLUENZA A VIRUS
• Total number of polymer chains: 4
• Total formula weight: 97485.50

Authors

Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.J.,Ruigrok, R.W.H.,Cusack, S. (deposition date: 2012-05-28, release date: 2012-08-22, Last modification date: 2023-12-20)

• Primary citation: Kowalinski, E.,Zubieta, C.,Wolkerstorfer, A.,Szolar, O.H.,Ruigrok, R.W.,Cusack, S.; Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.; Plos Pathog., 8:2831-, 2012; PubMed: 22876177; DOI: 10.1371/JOURNAL.PPAT.1002831

Experimental method

X-RAY DIFFRACTION (1.87 Å)