4AOU

CtIDH bound to NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism

4AOU の概要

• エントリーDOI: 10.2210/pdb4aou/pdb
• 関連するPDBエントリー: 4AOV
• 分子名称: ISOCITRATE DEHYDROGENASE [NADP], ISOCITRIC ACID, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, temperature adaptation, thermophilic, psychrophilic, nadp+ selectivity, domain movements
• 由来する生物種: CLOSTRIDIUM THERMOCELLUM
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46802.03

構造登録者

Leiros, H.-K.S.,Fedoy, A.-E.,Leiros, I.,Steen, I.H. (登録日: 2012-03-30, 公開日: 2012-07-11, 最終更新日: 2024-05-08)

• 主引用文献: Leiros, H.K.,Fedoy, A.E.,Leiros, I.,Steen, I.H.; The complex structures of isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila suggest a new active site locking mechanism.; Febs Open Bio, 2:159-172, 2012; PubMed: 23650595; DOI: 10.1016/j.fob.2012.06.003

実験手法

X-RAY DIFFRACTION (2.5 Å)