4AM0

Structure of Dengue virus strain 4 DIII in complex with Fab 2H12

Summary for 4AM0

• Entry DOI: 10.2210/pdb4am0/pdb
• Related: 4AL8 4ALA
• Descriptor: FAB 2H12, HEAVY CHAIN, FAB 2H12, LIGHT CHAIN, ENVELOPE PROTEIN, (3 entities in total)
• Functional Keywords: viral protein, antibody, neutralisation
• Biological source: HOMO SAPIENS (Human); More
• Total number of polymer chains: 12
• Total formula weight: 230664.90

Authors

Midgley, C.M.,Flanagan, A.,Mongkolsapaya, J.,Grimes, J.M.,Screaton, G.R. (deposition date: 2012-03-06, release date: 2012-06-06, Last modification date: 2019-12-04)

• Primary citation: Midgley, C.M.,Flanagan, A.,Tran, H.B.,Dejnirattisai, W.,Chawansuntati, K.,Jumnainsong, A.,Wongwiwat, W.,Duangchinda, T.,Mongkolsapaya, J.,Grimes, J.M.,Screaton, G.R.; Structural Analysis of a Dengue Cross-Reactive Antibody Complexed with Envelope Domain III Reveals the Molecular Basis of Cross-Reactivity.; J.Immunol., 188:4971-, 2012; PubMed: 22491255; DOI: 10.4049/JIMMUNOL.1200227

Experimental method

X-RAY DIFFRACTION (3.02 Å)