4AFL

The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.

Summary for 4AFL

Entry DOI	10.2210/pdb4afl/pdb
Related	2VNF
Descriptor	INHIBITOR OF GROWTH PROTEIN 4 (2 entities in total)
Functional Keywords	cell cycle, tumour suppressor, chromatin remodelling
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: Q9UNL4
Total number of polymer chains	6
Total formula weight	74407.46
Authors	Culurgioni, S.,Munoz, I.G.,Moreno, A.,Palacios, A.,Villate, M.,Palmero, I.,Montoya, G.,Blanco, F.J. (deposition date: 2012-01-19, release date: 2012-02-22, Last modification date: 2012-07-11)
Primary citation	Culurgioni, S.,Munoz, I.G.,Moreno, A.,Palacios, A.,Villate, M.,Palmero, I.,Montoya, G.,Blanco, F.J. Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins. J.Biol.Chem., 287:10876-, 2012 Cited by PubMed: 22334692 DOI: 10.1074/JBC.M111.330001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.275 Å)

Structure validation