4AFL
The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.
Summary for 4AFL
Entry DOI | 10.2210/pdb4afl/pdb |
Related | 2VNF |
Descriptor | INHIBITOR OF GROWTH PROTEIN 4 (2 entities in total) |
Functional Keywords | cell cycle, tumour suppressor, chromatin remodelling |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: Q9UNL4 |
Total number of polymer chains | 6 |
Total formula weight | 74407.46 |
Authors | Culurgioni, S.,Munoz, I.G.,Moreno, A.,Palacios, A.,Villate, M.,Palmero, I.,Montoya, G.,Blanco, F.J. (deposition date: 2012-01-19, release date: 2012-02-22, Last modification date: 2012-07-11) |
Primary citation | Culurgioni, S.,Munoz, I.G.,Moreno, A.,Palacios, A.,Villate, M.,Palmero, I.,Montoya, G.,Blanco, F.J. Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins. J.Biol.Chem., 287:10876-, 2012 Cited by PubMed: 22334692DOI: 10.1074/JBC.M111.330001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.275 Å) |
Structure validation
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