4AF8
The structural basis for metacaspase substrate specificity and activation
Summary for 4AF8
| Entry DOI | 10.2210/pdb4af8/pdb |
| Related | 4AFP 4AFR 4AFV |
| Descriptor | METACASPASE MCA2, SODIUM ION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | hydrolase, cysteine peptidase, caspase/hemoglobin fold |
| Biological source | TRYPANOSOMA BRUCEI |
| Total number of polymer chains | 1 |
| Total formula weight | 40135.20 |
| Authors | McLuskey, K.,Rudolf, J.,Isaacs, N.W.,Coombs, G.H.,Moss, C.X.,Mottram, J.C. (deposition date: 2012-01-18, release date: 2012-05-02, Last modification date: 2024-05-01) |
| Primary citation | Mcluskey, K.,Rudolf, J.,Proto, W.R.,Isaacs, N.W.,Coombs, G.H.,Moss, C.X.,Mottram, J.C. Crystal Structure of a Trypanosoma Brucei Metacaspase. Proc.Natl.Acad.Sci.USA, 109:7469-, 2012 Cited by PubMed: 22529389DOI: 10.1073/PNAS.1200885109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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