4AEI

Crystal structure of the AaHII-Fab4C1 complex

4AEI の概要

• エントリーDOI: 10.2210/pdb4aei/pdb
• 関連するPDBエントリー: 1AHO 1PTX 1SEG 4AEH
• 分子名称: ALPHA-MAMMAL TOXIN AAH2, FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN, ... (6 entities in total)
• 機能のキーワード: immune system-toxin complex, alpha-toxin, conformational rearrangement, combining site, epitope, pharmacological site, venom, voltage-activated sodium channel, immune system/toxin
• 由来する生物種: ANDROCTONUS AUSTRALIS HECTOR (FAT-TAILED SCORPION); 詳細
• 細胞内の位置: Secreted: P01484
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 169166.50

構造登録者

Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P. (登録日: 2012-01-10, 公開日: 2012-03-07, 最終更新日: 2023-12-20)

• 主引用文献: Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P.; Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom; J.Biol.Chem., 287:14136-, 2012; PubMed: 22371498; DOI: 10.1074/JBC.M111.315382

実験手法

X-RAY DIFFRACTION (2.3 Å)