4A6A

A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP

4A6A の概要

• エントリーDOI: 10.2210/pdb4a6a/pdb
• 分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: hydrolase, deoxy-ribonucleotide metabolism, dttp inhibition
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 257162.16

構造登録者

Lovgreen, M.N.,Ucar, E.,Willemoes, M.,Harris, P. (登録日: 2011-11-01, 公開日: 2012-10-10, 最終更新日: 2017-11-08)

• 主引用文献: Lovgreen, M.N.,Harris, P.,Ucar, E.,Willemoes, M.; Dttp Inhibition of the Bifunctional Dctp Deaminase- Dutpase from Mycobacterium Tuberculosis is Ph Dependent: Kinetic Analyses and Crystal Structure of A115V Variant; To be Published,

実験手法

X-RAY DIFFRACTION (2.9 Å)