4A65
Crystal structure of the thioredoxin reductase from Entamoeba histolytica with AuCN
Summary for 4A65
Entry DOI | 10.2210/pdb4a65/pdb |
Related | 4A5L |
Descriptor | THIOREDOXIN REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GOLD ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase, redox metabolism, oxidative stress |
Biological source | ENTAMOEBA HISTOLYTICA |
Total number of polymer chains | 2 |
Total formula weight | 71207.20 |
Authors | Podust, L.M. (deposition date: 2011-10-31, release date: 2012-11-07, Last modification date: 2023-12-20) |
Primary citation | Parsonage, D.,Sheng, F.,Hirata, K.,Debnath, A.,Mckerrow, J.H.,Reed, S.L.,Abagyan, R.,Poole, L.B.,Podust, L.M. X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194:180-, 2016 Cited by PubMed: 26876147DOI: 10.1016/J.JSB.2016.02.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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