4A4M
Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)
Summary for 4A4M
Entry DOI | 10.2210/pdb4a4m/pdb |
Related | 1BOJ 1BOK 1EDS 1EDV 1EDW 1EDX 1F88 1FDF 1GZM 1HZX 1JFP 1L9H 1LN6 1N3M 1NZS 1OV0 1OV1 1U19 1VQX 2I35 2I36 2I37 2J4Y 2X72 |
Descriptor | RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | signaling protein, g-protein, g-protein-coupled receptors, signal tansduction, visual system, metarhodopsin-ii |
Biological source | BOS TAURUS (BOVINE) More |
Total number of polymer chains | 2 |
Total formula weight | 41648.74 |
Authors | Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.D.,Schertler, G.F.X.,Standfuss, J. (deposition date: 2011-10-17, release date: 2012-01-25, Last modification date: 2023-12-20) |
Primary citation | Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.,Schertler, G.,Standfuss, J. Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II. Proc.Natl.Acad.Sci.USA, 109:119-, 2012 Cited by PubMed: 22198838DOI: 10.1073/PNAS.1114089108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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