4A4M

Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)

Summary for 4A4M

Entry DOI	10.2210/pdb4a4m/pdb
Related	1BOJ 1BOK 1EDS 1EDV 1EDW 1EDX 1F88 1FDF 1GZM 1HZX 1JFP 1L9H 1LN6 1N3M 1NZS 1OV0 1OV1 1U19 1VQX 2I35 2I36 2I37 2J4Y 2X72
Descriptor	RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	signaling protein, g-protein, g-protein-coupled receptors, signal tansduction, visual system, metarhodopsin-ii
Biological source	BOS TAURUS (BOVINE) More
Total number of polymer chains	2
Total formula weight	41648.74
Authors	Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.D.,Schertler, G.F.X.,Standfuss, J. (deposition date: 2011-10-17, release date: 2012-01-25, Last modification date: 2023-12-20)
Primary citation	Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.,Schertler, G.,Standfuss, J. Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II. Proc.Natl.Acad.Sci.USA, 109:119-, 2012 Cited by PubMed: 22198838 DOI: 10.1073/PNAS.1114089108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation