4A4M

Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)

4A4M の概要

• エントリーDOI: 10.2210/pdb4a4m/pdb
• 関連するPDBエントリー: 1BOJ 1BOK 1EDS 1EDV 1EDW 1EDX 1F88 1FDF 1GZM 1HZX 1JFP 1L9H 1LN6 1N3M 1NZS 1OV0 1OV1 1U19 1VQX 2I35 2I36 2I37 2J4Y 2X72
• 分子名称: RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: signaling protein, g-protein, g-protein-coupled receptors, signal tansduction, visual system, metarhodopsin-ii
• 由来する生物種: BOS TAURUS (BOVINE); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41648.74

構造登録者

Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.D.,Schertler, G.F.X.,Standfuss, J. (登録日: 2011-10-17, 公開日: 2012-01-25, 最終更新日: 2023-12-20)

• 主引用文献: Deupi, X.,Edwards, P.,Singhal, A.,Nickle, B.,Oprian, D.,Schertler, G.,Standfuss, J.; Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.; Proc.Natl.Acad.Sci.USA, 109:119-, 2012; PubMed: 22198838; DOI: 10.1073/PNAS.1114089108

実験手法

X-RAY DIFFRACTION (3.3 Å)