4A2X
Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA
Summary for 4A2X
Entry DOI | 10.2210/pdb4a2x/pdb |
Related | 4A2P 4A2Q 4A2V 4A2W 4A36 |
Descriptor | RETINOIC ACID INDUCIBLE PROTEIN I, 5'-R(*GP*GP*GP*AP*GP*AP*AP*CP*AP*AP*CP*GP*CP*GP)-3', 5'-R(*CP*GP*CP*GP*UP*UP*GP*UP*UP*CP*UP*CP*CP*CP)-3', ... (4 entities in total) |
Functional Keywords | rna binding protein-rna complex, superfamily 2 rna helicase, atp and dsrna binding, antiviral signalling pathway, rna binding protein/rna |
Biological source | ANAS PLATYRHYNCHOS (MALLARD DUCK) More |
Total number of polymer chains | 8 |
Total formula weight | 78868.67 |
Authors | Kowalinski, E.,Lunardi, T.,McCarthy, A.A.,Cusack, S. (deposition date: 2011-09-29, release date: 2011-10-19, Last modification date: 2023-12-20) |
Primary citation | Kowalinski, E.,Lunardi, T.,McCarthy, A.A.,Louber, J.,Brunel, J.,Grigorov, B.,Gerlier, D.,Cusack, S. Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell, 147:423-435, 2011 Cited by PubMed: 22000019DOI: 10.1016/j.cell.2011.09.039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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