4A21

Structure of Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase bound to sulfate

4A21 の概要

• エントリーDOI: 10.2210/pdb4a21/pdb
• 関連するPDBエントリー: 4A22
• 分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE, SULFATE ION, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: hydrolase, fbp aldolase, class ii, inhibitor, lyase, lyase-lyase inhibitor complex
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 147156.00

構造登録者

Coincon, M.,De la Paz Santangelo, M.,Gest, P.M.,Guerin, M.E.,Pham, H.,Ryan, G.,Puckett, S.E.,Spencer, J.S.,Gonzalez-Juarrero, M.,Daher, R.,Lenaerts, A.J.,Schnappinger, D.,Therisod, M.,Ehrt, S.,Jackson, M.,Sygusch, J. (登録日: 2011-09-21, 公開日: 2011-10-05, 最終更新日: 2011-11-30)

• 主引用文献: De La Paz Santangelo, M.,Gest, P.M.,Guerin, M.E.,Coincon, M.,Pham, H.,Ryan, G.,Puckett, S.E.,Spencer, J.S.,Gonzalez-Juarrero, M.,Daher, R.,Lenaerts, A.J.,Schnappinger, D.,Therisod, M.,Ehrt, S.,Sygusch, J.,Jackson, M.; Glycolytic and Non-Glycolytic Functions of the Fructose-1,6-Bisphosphate Aldolase of Mycobacterium Tuberculosis, an Essential Enzyme Produced by Replicating and Non-Replicating Bacilli; J.Biol.Chem., 286:40219-, 2011; PubMed: 21949126; DOI: 10.1074/JBC.M111.259440

実験手法

X-RAY DIFFRACTION (2.35 Å)