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4ZJ3

Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant.

Summary for 4ZJ3
Entry DOI10.2210/pdb4zj3/pdb
Related4ZJ1 4ZJ2
DescriptorBeta-lactamase TEM (2 entities in total)
Functional Keywordsnoncanonical amino acid, beta-lactamase, protein evolution, evolutionary advantage, hydrolase
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight33328.12
Authors
Xiao, H.,Nasertorabi, F.,Choi, S.,Han, G.W.,Reed, S.A.,Stevens, R.C.,Schultz, P.G. (deposition date: 2015-04-29, release date: 2015-05-20, Last modification date: 2023-11-15)
Primary citationXiao, H.,Nasertorabi, F.,Choi, S.H.,Han, G.W.,Reed, S.A.,Stevens, R.C.,Schultz, P.G.
Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112:6961-6966, 2015
Cited by
PubMed: 26038548
DOI: 10.1073/pnas.1507741112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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