4Z9O
Crystal Structure of human GGT1
Summary for 4Z9O
Entry DOI | 10.2210/pdb4z9o/pdb |
Descriptor | Gamma-glutamyltranspeptidase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total) |
Functional Keywords | ntn-hydrolase family, glycoprotein, n- glycosylation, cell surface, hydrolase, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 60359.72 |
Authors | Terzyan, S.S.,Hanigan, M.H. (deposition date: 2015-04-10, release date: 2015-06-03, Last modification date: 2020-07-29) |
Primary citation | Terzyan, S.S.,Burgett, A.W.,Heroux, A.,Smith, C.A.,Mooers, B.H.,Hanigan, M.H. Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS. J.Biol.Chem., 290:17576-17586, 2015 Cited by PubMed: 26013825DOI: 10.1074/jbc.M115.659680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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