4Z7O
Integrin alphaIIbbeta3 in complex with AGDV peptide
Summary for 4Z7O
Entry DOI | 10.2210/pdb4z7o/pdb |
Related | 4Z7N 4Z7Q 4Z7S |
Descriptor | Integrin alpha-IIb, CALCIUM ION, MANGANESE (II) ION, ... (14 entities in total) |
Functional Keywords | cell adhesion, platelet aggregation, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P08514 Cell membrane ; Single- pass type I membrane protein : P05106 |
Total number of polymer chains | 10 |
Total formula weight | 301168.52 |
Authors | Lin, F.Y.,Zhu, J.,Springer, T.A. (deposition date: 2015-04-07, release date: 2016-01-27, Last modification date: 2020-07-29) |
Primary citation | Lin, F.Y.,Zhu, J.,Eng, E.T.,Hudson, N.E.,Springer, T.A. beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece. J.Biol.Chem., 291:4537-4546, 2016 Cited by PubMed: 26631735DOI: 10.1074/jbc.M115.705624 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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