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4Z7O

Integrin alphaIIbbeta3 in complex with AGDV peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Integrin alpha-IIbpolymer45549357.82UniProt (P08514)
Pfam (PF01839)
Homo sapiens (Human)GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb
2B, D
(B, D)
Integrin beta-3polymer46951804.62UniProt (P05106)
Pfam (PF17205)
Pfam (PF00362)
Pfam (PF18372)
Homo sapiens (Human)Platelet membrane glycoprotein IIIa,GPIIIa
3E, G
(E, H)
Monoclonal antibody 10E5 Fab heavy chainpolymer22123766.52Mus musculus
4F, H
(F, L)
Monoclonal antibody 10E5 Fab light chainpolymer21423332.72Mus musculus
5I, J
(G, I)
Tetrapeptide ALA-GLY-ASP-VALpolymer4360.42Homo sapiens
6K
(J)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
7L, N
(K, N)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
8M
(M)
alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G81315DD)
9HA, O, X
(L, A, C)
SULFATE IONnon-polymer96.13Chemie (SO4)
10AA, BA, CA, P, Q...
(C, A)
CALCIUM IONnon-polymer40.18Chemie (CA)
11DA, EA, FA, T, U...
(D, B)
MANGANESE (II) IONnon-polymer54.96Chemie (MN)
12GA, W
(D, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
13Y
(C)
CHLORIDE IONnon-polymer35.51Chemie (CL)
14IA, JA, KA, LA, MA...
(A, B, C, D, E...)
waterwater18.0584Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight297243.9
BranchedNumber of molecules4
Total formula weight2508.3
Non-Polymers*Number of molecules20
Total formula weight1416.3
All*Total formula weight301168.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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