4YZ2
Crystal Structure of Streptococcus pneumoniae NanC, in complex with 2-deoxy-2,3-didehydro-N-acetylneuraminic acid.
Summary for 4YZ2
Entry DOI | 10.2210/pdb4yz2/pdb |
Descriptor | Sialidase NanC, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | sialidase, neuraminidase, beta-propeller, cbm40, hydrolase |
Biological source | Streptococcus pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 153536.83 |
Authors | Lukacik, P.,Owen, C.D.,Potter, J.A.,Taylor, G.L.,Walsh, M.A. (deposition date: 2015-03-24, release date: 2015-09-23, Last modification date: 2024-05-08) |
Primary citation | Owen, C.D.,Lukacik, P.,Potter, J.A.,Sleator, O.,Taylor, G.L.,Walsh, M.A. Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290:27736-27748, 2015 Cited by PubMed: 26370075DOI: 10.1074/jbc.M115.673632 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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