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4YQW

Mutant Human DNA Polymerase Eta Q38A/R61A Inserting dCTP Opposite Template G

Summary for 4YQW
Entry DOI10.2210/pdb4yqw/pdb
Related4YR0 4YR2 4YR3
DescriptorDNA polymerase eta, DNA (5'-D(*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
Functional Keywordsdctp template g, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight55295.06
Authors
Su, Y.,Patra, A.,Harp, J.M.,Egli, M.,Guengerich, F.P. (deposition date: 2015-03-13, release date: 2015-05-13, Last modification date: 2023-09-27)
Primary citationSu, Y.,Patra, A.,Harp, J.M.,Egli, M.,Guengerich, F.P.
Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase eta in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.
J.Biol.Chem., 290:15921-15933, 2015
Cited by
PubMed: 25947374
DOI: 10.1074/jbc.M115.653691
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.064 Å)
Structure validation

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