4YJ5
Crystal structure of PKM2 mutant
Summary for 4YJ5
Entry DOI | 10.2210/pdb4yj5/pdb |
Descriptor | Pyruvate kinase PKM, PYRUVIC ACID, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | pkm2 mutant, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 228619.47 |
Authors | Liu, J.-S.,Wu, C.-W.,Wang, W.-C. (deposition date: 2015-03-03, release date: 2016-03-09, Last modification date: 2023-11-15) |
Primary citation | Chen, T.J.,Wang, H.J.,Liu, J.S.,Cheng, H.H.,Hsu, S.C.,Wu, M.C.,Lu, C.H.,Wu, Y.F.,Wu, J.W.,Liu, Y.Y.,Kung, H.J.,Wang, W.C. Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation Commun Biol, 2:-, 2019 Cited by DOI: 10.1038/s42003-019-0343-4PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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