4Y5O

CCM2 HHD in complex with MEKK3 NPB1

Summary for 4Y5O

Entry DOI	10.2210/pdb4y5o/pdb
Descriptor	Malcavernin, Mitogen-activated protein kinase kinase kinase 3 (3 entities in total)
Functional Keywords	complex, kinase, scaffold, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	25843.24
Authors	Fisher, O.S.,Boggon, T.J. (deposition date: 2015-02-11, release date: 2015-07-01, Last modification date: 2023-09-27)
Primary citation	Fisher, O.S.,Deng, H.,Liu, D.,Zhang, Y.,Wei, R.,Deng, Y.,Zhang, F.,Louvi, A.,Turk, B.E.,Boggon, T.J.,Su, B. Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun, 6:7937-7937, 2015 Cited by PubMed: 26235885 DOI: 10.1038/ncomms8937 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation