4Y5O

CCM2 HHD in complex with MEKK3 NPB1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Malcavernin	polymer	98	11162.6	1	UniProt (Q9BSQ5) Pfam (PF16545) In PDB	Homo sapiens (Human)	Cerebral cavernous malformations 2 protein
2	B	Mitogen-activated protein kinase kinase kinase 3	polymer	126	14680.6	1	UniProt (Q99759) Pfam (PF00564) In PDB	Homo sapiens (Human)	MAPK/ERK kinase kinase 3,MEKK 3
3		water	water		18.0	20	Chemie (HOH)

Sequence modifications

A: 283 - 379 (UniProt: Q9BSQ5)

PDB	External Database	Details
Gly 282	-	expression tag

B: 1 - 124 (UniProt: Q99759)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25843.2
All*	Total formula weight	25843.2

*Water molecules are not included.