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4Y5O

CCM2 HHD in complex with MEKK3 NPB1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Malcaverninpolymer9811162.61UniProt (Q9BSQ5)
Pfam (PF16545)
Homo sapiens (Human)Cerebral cavernous malformations 2 protein
2B
(B)
Mitogen-activated protein kinase kinase kinase 3polymer12614680.61UniProt (Q99759)
Pfam (PF00564)
Homo sapiens (Human)MAPK/ERK kinase kinase 3,MEKK 3
3C, D
(A, B)
waterwater18.020Chemie (HOH)
Sequence modifications
A: 283 - 379 (UniProt: Q9BSQ5)
PDBExternal DatabaseDetails
Gly 282-expression tag
B: 1 - 124 (UniProt: Q99759)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25843.2
All*Total formula weight25843.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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