4XS0

Human methemoglobin in complex with the second and third NEAT domains of IsdH(F365Y/A369F/Y642A) from Staphylococcus aureus

Summary for 4XS0

• Entry DOI: 10.2210/pdb4xs0/pdb
• Related: 4IJ2
• Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... (7 entities in total)
• Functional Keywords: neat, heme/hemoglobin binding, hemoglobin, oxygen transport-protein binding complex, oxygen transport, metal transport
• Biological source: Staphylococcus aureus; More
• Cellular location: Secreted, cell wall ; Peptidoglycan-anchor : Q2FG07
• Total number of polymer chains: 3
• Total formula weight: 71405.35

Authors

Dickson, C.F.,Jacques, D.A.,Guss, J.M.,Gell, D.A. (deposition date: 2015-01-21, release date: 2015-06-03, Last modification date: 2024-01-10)

• Primary citation: Dickson, C.F.,Jacques, D.A.,Clubb, R.T.,Guss, J.M.,Gell, D.A.; The structure of haemoglobin bound to the haemoglobin receptor IsdH from Staphylococcus aureus shows disruption of the native alpha-globin haem pocket.; Acta Crystallogr.,Sect.D, 71:1295-1306, 2015; PubMed: 26057669; DOI: 10.1107/S1399004715005817

Experimental method

X-RAY DIFFRACTION (2.55 Å)