4XS0
Human methemoglobin in complex with the second and third NEAT domains of IsdH(F365Y/A369F/Y642A) from Staphylococcus aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 1 | UniProt (P69905) Pfam (PF00042) In PDB | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | B | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 1 | UniProt (P68871) Pfam (PF00042) In PDB | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | C | Iron-regulated surface determinant protein H | polymer | 336 | 38929.4 | 1 | UniProt (Q2FG07) Pfam (PF05031) Pfam (PF20861) In PDB | Staphylococcus aureus | Haptoglobin receptor A,Staphylococcus aureus surface protein I |
| 4 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 5 | B, C | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | C | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
C: 326 - 660 (UniProt: Q2FG07)
| PDB | External Database | Details |
|---|---|---|
| Ser 325 | - | expression tag |
| Tyr 365 | Phe 365 | engineered mutation |
| Phe 369 | Ala 369 | engineered mutation |
| Ala 642 | Tyr 642 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69970.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1435.4 | |
| All* | Total formula weight | 71405.3 |
