4X3I

The crystal structure of Arc N-lobe complexed with CAMK2A fragment

Summary for 4X3I

• Entry DOI: 10.2210/pdb4x3i/pdb
• Related: 4X3H 4X3X
• Descriptor: Activity-regulated cytoskeleton-associated protein, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA (3 entities in total)
• Functional Keywords: endocytosis mediator, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cytoplasm, cytoskeleton: Q63053
• Total number of polymer chains: 2
• Total formula weight: 10146.03

Authors

Zhang, W.,Ward, M.,Leahy, D.,Worley, P. (deposition date: 2014-11-30, release date: 2015-06-03, Last modification date: 2017-09-27)

• Primary citation: Zhang, W.,Wu, J.,Ward, M.D.,Yang, S.,Chuang, Y.A.,Xiao, M.,Li, R.,Leahy, D.J.,Worley, P.F.; Structural basis of arc binding to synaptic proteins: implications for cognitive disease.; Neuron, 86:490-500, 2015; PubMed: 25864631; DOI: 10.1016/j.neuron.2015.03.030

Experimental method

X-RAY DIFFRACTION (1.8 Å)