4WVJ

Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with an inhibitor peptide (pep3).

Summary for 4WVJ

Entry DOI	10.2210/pdb4wvj/pdb
Related	4WVG 4WVH 4WVI
Related PRD ID	PRD_900001
Descriptor	Maltose-binding periplasmic protein,Signal peptidase IB, inhibitor peptide (PEP3), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywords	spsb type-i signal peptidase peptide inhibitor complex cell secretion s. aureus mbp fusion, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli K-12 More
Total number of polymer chains	2
Total formula weight	60689.36
Authors	Young, P.G.,Ting, Y.T.,Baker, E.N. (deposition date: 2014-11-05, release date: 2015-09-23, Last modification date: 2023-09-27)
Primary citation	Ting, Y.T.,Harris, P.W.,Batot, G.,Brimble, M.A.,Baker, E.N.,Young, P.G. Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization. IUCrJ, 3:10-19, 2016 Cited by PubMed: 26870377 DOI: 10.1107/S2052252515019971 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation