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4WRF

Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Mannose

Summary for 4WRF
Entry DOI10.2210/pdb4wrf/pdb
Related4WR9 4WRC 4WRE
DescriptorPulmonary surfactant-associated protein A, CALCIUM ION, alpha-D-mannopyranose, ... (6 entities in total)
Functional Keywordscollectin, carbohydrate binding, lectin, lipid binding, sugar binding protein
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains1
Total formula weight17087.39
Authors
Rynkiewicz, M.J.,Wu, H.,Cafarella, T.R.,Nikolaidis, N.M.,Head, J.F.,Seaton, B.A.,McCormack, F.X. (deposition date: 2014-10-23, release date: 2016-02-10, Last modification date: 2024-10-23)
Primary citationRynkiewicz, M.J.,Wu, H.,Cafarella, T.R.,Nikolaidis, N.M.,Head, J.F.,Seaton, B.A.,McCormack, F.X.
Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
To be published,
Experimental method
X-RAY DIFFRACTION (1.901 Å)
Structure validation

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