4WKV
n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ
Summary for 4WKV
Entry DOI | 10.2210/pdb4wkv/pdb |
Related | 4WKS 4WKT 4WKU |
Descriptor | Acyl-homoserine lactone acylase PvdQ, trihydroxy(octyl)borate(1-), GLYCEROL, ... (5 entities in total) |
Functional Keywords | n-alkylboronic acid inhibitors of pvdq, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Pseudomonas aeruginosa More |
Cellular location | Periplasm : Q9I194 Q9I194 |
Total number of polymer chains | 2 |
Total formula weight | 80181.73 |
Authors | Wu, R.,Clevenger, K.D.,Fast, W.,Liu, D. (deposition date: 2014-10-03, release date: 2014-11-12, Last modification date: 2023-12-27) |
Primary citation | Clevenger, K.D.,Wu, R.,Liu, D.,Fast, W. n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ. Biochemistry, 53:6679-6686, 2014 Cited by PubMed: 25290020DOI: 10.1021/bi501086s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1434 Å) |
Structure validation
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