4WKS

n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ

Summary for 4WKS

Entry DOI	10.2210/pdb4wks/pdb
Related	4WKT 4WKU 4WKV
Descriptor	Acyl-homoserine lactone acylase PvdQ, ethylboronic acid, ... (4 entities in total)
Functional Keywords	pvdq, n-alkylboronic acid, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Pseudomonas aeruginosa More
Cellular location	Periplasm : Q9I194 Q9I194
Total number of polymer chains	2
Total formula weight	78699.16
Authors	Wu, R.,Clevenger, D.K.,Fast, W.,Liu, D. (deposition date: 2014-10-03, release date: 2014-11-12, Last modification date: 2023-09-27)
Primary citation	Clevenger, K.D.,Wu, R.,Liu, D.,Fast, W. n-Alkylboronic Acid Inhibitors Reveal Determinants of Ligand Specificity in the Quorum-Quenching and Siderophore Biosynthetic Enzyme PvdQ. Biochemistry, 53:6679-6686, 2014 Cited by PubMed: 25290020 DOI: 10.1021/bi501086s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.629 Å)

Structure validation