4P6F
Crystal structure of the peptolide 12C bound to bacterial ribosome
This is a non-PDB format compatible entry.
Summary for 4P6F
Entry DOI | 10.2210/pdb4p6f/pdb |
Descriptor | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (59 entities in total) |
Functional Keywords | protein biosynthesis, ribosome, rna, trna, peptide exit tunnel, macrolide, ribosome-ribosome inhibitor complex, ribosome/ribosome inhibitor |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 114 |
Total formula weight | 4523029.85 |
Authors | Fagan, C.E.,Dunham, C.M. (deposition date: 2014-03-24, release date: 2014-10-01, Last modification date: 2023-09-27) |
Primary citation | Washington, A.Z.,Benicewicz, D.B.,Canzoneri, J.C.,Fagan, C.E.,Mwakwari, S.C.,Maehigashi, T.,Dunham, C.M.,Oyelere, A.K. Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome. Acs Chem.Biol., 9:2621-2631, 2014 Cited by PubMed: 25198768DOI: 10.1021/cb5003224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
Download full validation report