4URO

Crystal Structure of Staph GyraseB 24kDa in complex with Novobiocin

Summary for 4URO

• Entry DOI: 10.2210/pdb4uro/pdb
• Related: 4URL 4URM 4URN
• Descriptor: DNA GYRASE SUBUNIT B, NOVOBIOCIN (3 entities in total)
• Functional Keywords: isomerase, antibiotics, topoisomerase iv, natural product
• Biological source: STAPHYLOCOCCUS AUREUS
• Cellular location: Cytoplasm (Potential): P0A0K8
• Total number of polymer chains: 4
• Total formula weight: 105204.97

Authors

Lu, J.,Patel, S.,Sharma, N.,Soisson, S.,Kishii, R.,Takei, M.,Fukuda, Y.,Lumb, K.J.,Singh, S.B. (deposition date: 2014-07-01, release date: 2014-07-30, Last modification date: 2024-01-10)

• Primary citation: Lu, J.,Patel, S.,Sharma, N.,Soisson, S.M.,Kishii, R.,Takei, M.,Fukuda, Y.,Lumb, K.J.,Singh, S.B.; Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.; Acs Chem.Biol., 9:2023-, 2014; PubMed: 24992706; DOI: 10.1021/CB5001197

Experimental method

X-RAY DIFFRACTION (2.59 Å)