4UNE

Human insulin B26Phe mutant crystal structure

Summary for 4UNE
Related4UNG 4UNH
DescriptorINSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION, ... (4 entities in total)
Functional Keywordshormone, b26 site
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight11795.43
Authors
Zakova, L.,Klevtikova, E.,Lepsik, M.,Collinsova, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. (deposition date: 2014-05-28, release date: 2014-10-15, Last modification date: 2018-05-16)
Primary citationBrzozowski, A.M.,Collinsova, M.,Jiracek, J.,Klevtikova, E.,Lepsik, M.,Turkenburg, J.P.,Watson, C.J.,Zakova, L.
Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70:2765-, 2014
PubMed: 25286859
DOI: 110.1107/S1399004714017775
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.59 Å)
Structure validation
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PDB entries from 2021-06-16