4UNE
Human insulin B26Phe mutant crystal structure
Summary for 4UNE
Entry DOI | 10.2210/pdb4une/pdb |
Related | 4UNG 4UNH |
Descriptor | INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hormone, b26 site |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 11795.43 |
Authors | Zakova, L.,Klevtikova, E.,Lepsik, M.,Collinsova, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. (deposition date: 2014-05-28, release date: 2014-10-15, Last modification date: 2024-01-10) |
Primary citation | Zakova, L.,Klevtikova, E.,Lepsik, M.,Collinsova, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70:2765-, 2014 Cited by PubMed: 25286859DOI: 10.1107/S1399004714017775 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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