4UMN

Structure of a stapled peptide antagonist bound to Nutlin-resistant Mdm2.

Summary for 4UMN

Entry DOI	10.2210/pdb4umn/pdb
Descriptor	E3 ubiquitin-protein ligase Mdm2, M06 (3 entities in total)
Functional Keywords	cell cycle
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	30154.52
Authors	Chee, S.,Wongsantichon, J.,Quah, S.,Robinson, R.C.,Verma, C.,Lane, D.P.,Brown, C.J.,Ghadessy, F.J. (deposition date: 2014-05-20, release date: 2014-05-28, Last modification date: 2024-02-07)
Primary citation	Chee, S.M.,Wongsantichon, J.,Soo Tng, Q.,Robinson, R.,Joseph, T.L.,Verma, C.,Lane, D.P.,Brown, C.J.,Ghadessy, F.J. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2. PLoS ONE, 9:e104914-e104914, 2014 Cited by PubMed: 25115702 DOI: 10.1371/journal.pone.0104914 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation