4TT2
Crystal structure of ATAD2A bromodomain complexed with H4(1-20)K5Ac peptide
Summary for 4TT2
Entry DOI | 10.2210/pdb4tt2/pdb |
Related | 4TT4 4TT6 4TTE 4TU4 4TU6 |
Descriptor | ATPase family AAA domain-containing protein 2, Histone H4K5Ac (3 entities in total) |
Functional Keywords | bromodomain-acetylated histone complex, gene regulation |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q6PL18 |
Total number of polymer chains | 2 |
Total formula weight | 16057.16 |
Authors | Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.,Leonard, P.,Geck Do, M.,Cardozo, M.,Palmer, W.,Andersen, J.,Jones, P.,Ladbury, J. (deposition date: 2014-06-19, release date: 2014-12-24, Last modification date: 2023-12-27) |
Primary citation | Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.P.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.R.,Leonard, P.G.,Geck Do, M.K.,Cardozo, M.G.,Andersen, J.N.,Palmer, W.S.,Jones, P.,Ladbury, J.E. Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem.J., 466:337-346, 2015 Cited by PubMed: 25486442DOI: 10.1042/BJ20140933 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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