4U25
Crystal structure of the E. coli ribosome bound to virginiamycin M1.
This is a non-PDB format compatible entry.
Summary for 4U25
Entry DOI | 10.2210/pdb4u25/pdb |
Descriptor | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (57 entities in total) |
Functional Keywords | protein biosynthesis, ribosome, rna, transfer, exit, peptidyl, 30s, 70s, 16s, ribosomal subunit, antibiotic, streptogramin |
Biological source | Escherichia coli str. K-12 substr. MDS42 More |
Total number of polymer chains | 105 |
Total formula weight | 4268914.32 |
Authors | Noeske, J.,Huang, J.,Olivier, N.B.,Giacobbe, R.A.,Zambrowski, M.,Cate, J.H.D. (deposition date: 2014-07-16, release date: 2014-07-30, Last modification date: 2023-12-27) |
Primary citation | Noeske, J.,Huang, J.,Olivier, N.B.,Giacobbe, R.A.,Zambrowski, M.,Cate, J.H. Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58:5269-5279, 2014 Cited by PubMed: 24957822DOI: 10.1128/AAC.03389-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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