4TLN
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Summary for 4TLN
Entry DOI | 10.2210/pdb4tln/pdb |
Descriptor | THERMOLYSIN, CALCIUM ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | hydrolase (metalloproteinase) |
Biological source | Bacillus thermoproteolyticus |
Total number of polymer chains | 1 |
Total formula weight | 34734.21 |
Authors | Matthews, B.W.,Holmes, M.A. (deposition date: 1982-02-08, release date: 1982-05-26, Last modification date: 2024-05-22) |
Primary citation | Holmes, M.A.,Matthews, B.W. Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20:6912-6920, 1981 Cited by PubMed: 7317361DOI: 10.1021/bi00527a026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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