4TKS
Native-SAD phasing for human EGFR kinase domain.
Summary for 4TKS
Entry DOI | 10.2210/pdb4tks/pdb |
Descriptor | Epidermal growth factor receptor (1 entity in total) |
Functional Keywords | egfr kinase domain, native-sad phasing, multiple crystals, low energy, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533 |
Total number of polymer chains | 1 |
Total formula weight | 37707.58 |
Authors | Cai, Z.,Greene, M.I.,Liu, Q. (deposition date: 2014-05-27, release date: 2014-10-08, Last modification date: 2023-12-27) |
Primary citation | Liu, Q.,Guo, Y.,Chang, Y.,Cai, Z.,Assur, Z.,Mancia, F.,Greene, M.I.,Hendrickson, W.A. Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70:2544-2557, 2014 Cited by PubMed: 25286840DOI: 10.1107/S1399004714013376 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2017 Å) |
Structure validation
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