4SKN

A NUCLEOTIDE-FLIPPING MECHANISM FROM THE STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE BOUND TO DNA

Summary for 4SKN

• Entry DOI: 10.2210/pdb4skn/pdb
• Descriptor: DNA (5'-D(*TP*GP*GP*GP*(D1P)P*GP*GP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*GP*CP*CP*GP*CP*CP*C)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE), ... (5 entities in total)
• Functional Keywords: dna glycosylase, dna base excision repair, uracil, dna, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051
• Total number of polymer chains: 3
• Total formula weight: 31697.19

Authors

Slupphaug, G.,Mol, C.D.,Kavli, B.,Arvai, A.S.,Krokan, H.E.,Tainer, J.A. (deposition date: 1999-02-20, release date: 1999-02-26, Last modification date: 2023-09-20)

• Primary citation: Slupphaug, G.,Mol, C.D.,Kavli, B.,Arvai, A.S.,Krokan, H.E.,Tainer, J.A.; A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA.; Nature, 384:87-92, 1996; PubMed: 8900285; DOI: 10.1038/384087a0

Experimental method

X-RAY DIFFRACTION (2.9 Å)