Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4S1R

Crystal structure of a VRC01-lineage antibody, 45-VRC01.H08.F-117225, in complex with clade A/E HIV-1 gp120 core

Summary for 4S1R
Entry DOI10.2210/pdb4s1r/pdb
Related4S1Q 4S1S
Descriptorclade A/E 93TH057 HIV-1 gp120 core, Fab of VRC01-lineage antibody,45-VRC01.H08.F-117225 heavy chain, Fab of VRC01 light chain, ... (4 entities in total)
Functional Keywordshiv-1, neutralizing antibodies, vrc01-lineage, antibody maturation, evolutionary rate, viral protein-immune system-inhibitor complex, viral protein/immune system/inhibitor
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
More
Total number of polymer chains3
Total formula weight89851.62
Authors
Kwon, Y.D.,Yang, Y.,Zhang, B.,Kwong, P.D. (deposition date: 2015-01-14, release date: 2015-04-22, Last modification date: 2023-09-20)
Primary citationWu, X.,Zhang, Z.,Schramm, C.A.,Joyce, M.G.,Do Kwon, Y.,Zhou, T.,Sheng, Z.,Zhang, B.,O'Dell, S.,McKee, K.,Georgiev, I.S.,Chuang, G.Y.,Longo, N.S.,Lynch, R.M.,Saunders, K.O.,Soto, C.,Srivatsan, S.,Yang, Y.,Bailer, R.T.,Louder, M.K.,Mullikin, J.C.,Connors, M.,Kwong, P.D.,Mascola, J.R.,Shapiro, L.
Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell(Cambridge,Mass.), 161:470-485, 2015
Cited by
PubMed: 25865483
DOI: 10.1016/j.cell.2015.03.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.214 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon