4RQ7

Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG)and dATP soaked with MgCl2 for 1hr

Summary for 4RQ7

• Entry DOI: 10.2210/pdb4rq7/pdb
• Related: 4RPX 4RPY 4RPZ 4RQ0 4RQ1 4RQ2 4RQ3 4RQ4 4RQ5 4RQ6 4RQ8
• Descriptor: DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*A)-3'), ... (8 entities in total)
• Functional Keywords: x-family, pol beta, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 49335.14

Authors

Vyas, R.,Reed, A.J.,Suo, Z. (deposition date: 2014-10-31, release date: 2015-04-15, Last modification date: 2023-09-20)

• Primary citation: Vyas, R.,Reed, A.J.,Tokarsky, E.J.,Suo, Z.; Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.; J.Am.Chem.Soc., 137:5225-5230, 2015; PubMed: 25825995; DOI: 10.1021/jacs.5b02109

Experimental method

X-RAY DIFFRACTION (2 Å)