4ROW
The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA
Summary for 4ROW
Entry DOI | 10.2210/pdb4row/pdb |
Related | 2JYW 4ROV |
Descriptor | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION (3 entities in total) |
Functional Keywords | zinc finger, dna deamination, dna binding, deamination, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9HC16 |
Total number of polymer chains | 1 |
Total formula weight | 23250.59 |
Authors | |
Primary citation | Lu, X.,Zhang, T.,Xu, Z.,Liu, S.,Zhao, B.,Lan, W.,Wang, C.,Ding, J.,Cao, C. Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA J.Biol.Chem., 290:4010-4021, 2015 Cited by PubMed: 25542899DOI: 10.1074/jbc.M114.624262 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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