4ROW
The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA dC->dU-editing enzyme APOBEC-3G | polymer | 198 | 23185.2 | 1 | UniProt (Q9HC16) Pfam (PF05240) In PDB | Homo sapiens (human) | APOBEC-related cytidine deaminase, APOBEC-related protein, ARCD, APOBEC-related protein 9, ARP-9, CEM-15, CEM15, Deoxycytidine deaminase, A3G |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 193 - 384 (UniProt: Q9HC16)
| PDB | External Database | Details |
|---|---|---|
| Gly 187 | - | expression tag |
| Ser 188 | - | expression tag |
| His 189 | - | expression tag |
| Met 190 | - | expression tag |
| Ala 191 | - | expression tag |
| Ser 192 | - | expression tag |
| Ala 370 | Asp 370 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23185.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 23250.6 |
