4RHG
Crystal structure of PTPN3 (PTPH1) D811E, C842S mutant in complex with Eps15 pTyr849 peptide
Summary for 4RHG
Entry DOI | 10.2210/pdb4rhg/pdb |
Related | 2B49 4RH5 4RH9 4RI4 4RI5 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 3, Epidermal growth factor receptor substrate 15 (3 entities in total) |
Functional Keywords | alpha beta, hydrolase, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 36069.70 |
Authors | Chen, K.-E.,Meng, T.C.,Wang, A.H.-J. (deposition date: 2014-10-02, release date: 2015-03-11, Last modification date: 2023-12-06) |
Primary citation | Chen, K.E.,Li, M.Y.,Chou, C.C.,Ho, M.R.,Chen, G.C.,Meng, T.C.,Wang, A.H. Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases. Structure, 23:653-664, 2015 Cited by PubMed: 25728925DOI: 10.1016/j.str.2015.01.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.581 Å) |
Structure validation
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