4R9W
Crystal structure of platelet factor 4 complexed with fondaparinux
Summary for 4R9W
Entry DOI | 10.2210/pdb4r9w/pdb |
Related | 4R97 4R9Y |
Related PRD ID | PRD_900028 |
Descriptor | Platelet factor 4, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside (3 entities in total) |
Functional Keywords | pf4, fondaparinux, cxc chemokine, platelet factor, glycosaminoglycan, platelet, cytokine |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 17072.65 |
Authors | Cai, Z.,Zhu, Z.,Liu, Q.,Greene, M.I. (deposition date: 2014-09-08, release date: 2015-12-16, Last modification date: 2020-07-29) |
Primary citation | Cai, Z.,Yarovoi, S.V.,Zhu, Z.,Rauova, L.,Hayes, V.,Lebedeva, T.,Liu, Q.,Poncz, M.,Arepally, G.,Cines, D.B.,Greene, M.I. Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6:8277-8277, 2015 Cited by PubMed: 26391892DOI: 10.1038/ncomms9277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report