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4Q9I

P-glycoprotein cocrystallised with QZ-Ala

Summary for 4Q9I
Entry DOI10.2210/pdb4q9i/pdb
Related4Q9H 4Q9J 4Q9K 4Q9L
Related PRD IDPRD_001236
DescriptorMultidrug resistance protein 1A, (30F)A(30F)A(30F)A Peptide (2 entities in total)
Functional Keywordsmembrane protein, transporter, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceMus musculus (mouse)
Cellular locationCell membrane; Multi-pass membrane protein: P21447
Total number of polymer chains3
Total formula weight143270.58
Authors
McGrath, A.P.,Szewczyk, P.,Chang, G. (deposition date: 2014-05-01, release date: 2015-03-04, Last modification date: 2023-11-15)
Primary citationSzewczyk, P.,Tao, H.,McGrath, A.P.,Villaluz, M.,Rees, S.D.,Lee, S.C.,Doshi, R.,Urbatsch, I.L.,Zhang, Q.,Chang, G.
Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71:732-741, 2015
Cited by
PubMed: 25760620
DOI: 10.1107/S1399004715000978
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.781 Å)
Structure validation

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